What is Peritoneal Metastasis Surgery (CRS)?
Peritoneal Metastasis Surgery, also known as Cytoreductive Surgery (CRS), is a highly specialized oncologic procedure designed to remove cancer that has spread to the peritoneum — the lining of the abdominal cavity.
These metastases often result from cancers such as:
-
Colon and rectal cancer
-
Appendix cancer (including mucinous tumors)
-
Ovarian cancer
-
Gastric cancer
-
Peritoneal mesothelioma
The goal of CRS is to remove all visible tumor deposits from abdominal organs and peritoneal surfaces.

Why is Cytoreductive Surgery Needed?
CRS is recommended for patients who have:
-
Peritoneal metastases (peritoneal carcinomatosis)
-
Tumor spread within the abdomen without distant organ involvement
-
Pseudomyxoma Peritonei (PMP)
-
Recurrent abdominal cancers causing ascites or discomfort
-
Appendix or colon cancer with mucin-producing tumors
-
Ovarian cancer with peritoneal spread
CRS can significantly improve survival when performed at experienced centers.
Types of Peritoneal Metastasis Surgery (CRS)
At Büyük Anadolu Hospital, our advanced surgical oncology team performs:
Complete Cytoreductive Surgery (CRS)
Removal of all visible tumor deposits using precise surgical techniques.
Peritonectomy Procedures
Removal of cancerous peritoneal surfaces in specific abdominal regions.
Omentectomy
Removal of the omentum when involved by metastases.
Organ-Specific Resections
If needed, tumors are removed from:
-
Colon
-
Small intestine
-
Spleen
-
Gallbladder
-
Diaphragm
-
Pelvic organs
Lymph Node Removal
For metastases involving regional lymph nodes.

How is CRS Performed?
- Performed under general anesthesia
- Duration: 4–10 hours, depending on tumor spread
- All visible tumor tissue is removed from abdominal surfaces
- Multiple organ resections may be required
- Specialized peritonectomy techniques are applied
- ICU monitoring for the first 24 hours
- Hospital stay: 7–10 days
- Early mobilization and respiratory exercises support recovery
Possible Risks & Our Preventive Measures
| Possible Risks | Our Preventive Measures |
|---|---|
| Infection | Prophylactic antibiotics & sterile surgical protocol |
| Bleeding | Advanced vessel-sealing & meticulous surgical planning |
| Anastomotic leakage | Careful bowel resections & postoperative monitoring |
| Bowel obstruction | Gentle tissue handling & early mobilization |
| Fluid accumulation | Drain placement & close monitoring |
| Nutritional imbalance | Dietitian-supported recovery plan |

Why Choose Büyük Anadolu Hospital for CRS?
- Experienced oncologic surgeons specializing in peritoneal metastasis
- Full capability for complex abdominal resections
- Advanced ICU support for safe recovery
- On-site imaging: CT, MRI, PET-CT for accurate staging
- Multidisciplinary cancer care (Surgery + Oncology + Radiology + Nutrition)
- Affordable treatment options for international patients
- Personalized treatment coordination from arrival to long-term follow-up
CRS Surgery FAQ
CRS removes visible tumors; HIPEC treats microscopic disease. Both are often combined.
In selected cases, yes — especially for PMP and early peritoneal metastasis.
Evaluation includes CT, MRI, PET-CT, tumor markers, and a PCI (Peritoneal Cancer Index) assessment.
Light activity in 3–4 weeks, full recovery in 6–10 weeks.
